Symptoms of pancreatic cancer What are the first signs. Symptoms of pancreatic cancer in women

Worldwide, the deaths of the fatal outcome of oncological diseases at their frequency occupy second place in the mortality list.

Leadership positions still remain for cardiovascular ailments.

To enormous regret, there are a lot of cases oncology ends with deaths, even despite the fact that modern doctors apply great efforts to find a medicine from the terrible "plague of 21 centuries."

One of the most terrible forms of illness is pancreatic cancer. As a rule, this ailment has a sad forecast for the fault that it is possible to diagnose it exclusively at the last stage of development.

The thing is that people do not pass on a regular basis of the survey, but turn to the doctor only when faced with very painful symptoms.

If you turn to statistics, the pancreatic cancer can be overcome more than 22 percent of patients.

These data were taken when registered, which determines the presence of pancreatic cancer at an early stage in 6 percent of people.

Causes of the development of ailment

Pancreas cancer develops under the influence of a number of factors. A great influence on this process has the environment and the wrong way of life of people.

Provice pancreatic cancer capable of the prejudition states of the body.

They are considered to include the development of chronic inflammation in the gland, adenoma, cystic lesions, hereditary pancreatitis of a recurrent nature.

With age, the likelihood of confirming the terrible diagnosis of pancreatic cancer increases. The risk group turns out to be people older than 55 years old.

An important impact on the development of pathology has smoking. Tobacco dependence provokes oncology and it is not just words.

Based on statistics, it is possible to say, pancreatic cancer occurs in smokers 2-3 times more often than people who do not have such a bad habit.

It is possible that other pathologies, for example, sugar diabetes, genetic predisposition, overweight, improper power, are capable of provoking the cancer of the pancreas head.

Negatively affect the person chemical carcinogens, such as asbestos, β-naphthylamine, benzidine.

It is important to conduct an active lifestyle, sitting work is also able to cause malfunctions in the body and launch the process of developing a terrible disease - the pancreatic head cancer, in fact, the same diagnosis can be confirmed if a person constantly uses alcohol.

Manifestation of oncology gland

The symptoms of the oncology of the gland increases as the tumor is gaining momentum.

In the early stages of the pancreatic head cancer, it may not be done at all.

Among the doctors there is such a saying, as "cancer does not hurt." Indeed, this fact carries a big danger, because potential patients do not seek help to the doctor on time.

The manifestation of the disease will be associated with the lack of appetite, attacks of fever, when the temperature regime of the patient's body increases sharply.

It is possible that a person will lose sharply, his skin will acquire a yellow shade. He can bother serious pain. Also, patients are very often complaining that the appetite disappears.

If we disassemble the symptoms of pancreatic cancer in more detail in women and men, it is worth noting that in the first place of the neoplasms make themselves know themselves. It will depend on the place of tumor concentration.

Similar first signs of pancreatic cancer are manifested in 75 percent of patients.

They arise due to the presses of the nerve trunks or the penetration of the tumor through the tissue shell.

Less frequently, the oncology of the pancreas can be a consequence of the blockage of the gallbladder ducts or is caused by peritonitis when the attack of the attack of pancreatitis is observed.

Inflammatory infection launches the development of a cancer process, which will later make himself felt in the form of pain syndrome.

The first symptoms of pain may provide a slope of the character or be spilled by the abdominal cavity, but also to have localization, giving up the right blade or back.

If a person complains about the pain of a conjunctive character, then a similar phenomenon is possible when the gallbladder is blocked by a tumor.

Gradually, painful syndrome will increase, and also will begin shirt. Often, such a development is inherent, if the pankreas head is affected.

Such symptoms of pancreatic cancer in women and men are found in 75 percent cases.

The sign is specific for this kind of pathology. It is due to the yellowing of the fact that it is observed bile in the system of biliary tract.

It provoked by the penetration of malignant sites, which fell into the dummy of the gallbladder.

In view of the fact that the symptom is not caused by the infectious process, this process is mechanical.

Every day, the jaundice is gradually enhanced. The symptoms of pancreatic cancer at the next stage of the development of pathology are reduced to the fact that the covers acquire a red shade, due to the accumulation of bilirubin.

It continues to oxidize, and therefore the skin acquires a greenish tint. Bile acids are capable of irritating the receptors of the skin, the disease is noticeably progresses.

If the symptoms of the pancreatic cancer in earlier stages may not appear, then later they become so bright that itch does not give a person to live quietly.

Itching provokes nervous bursts, does not even give to sleep well. On the skin there may be traces of combs, which are presented in multiple form.

There is a sharp discharge of weight, the patient ceases to experience the desire to eat even favorite products.

It is also noticed that meat or fatty food seems to be a man disgusting, the apathetic is growing, as well as weakness in the whole body.

Sometimes, there may be bouts of vomiting or nausea. But the sequence of what can be the oncology of the gland is symptoms, changes.

Itching can be the first sign of cancer, arising before the yellowing of the skin. There are such situations where initially a person sharply begins to lose weight.

Features of the structure of the gland

The importance of the pancreas should not be underestimated. The organ enters the system of the digestive system, responsible for multiple functions.

It is characterized by what has the same structure, both in men and women. Iron is not a steam room, developing food enzymes, and also responsible for the production of insulin.

Its device is in the structure of the body, tail and heads. The body of the organ will lay down to the wall of the stomach, the tail to the spleen, and the head to the 12-tupest intestine.

Therefore, depending on which part of the body is defective, a subsequent violation of the work and the structure of neighboring bodies will arise.

As practice shows, in 70 percent cases, a malignant tumor is located in the head of the pancreatic gland.

It develops on the basis of the epithelium. From statistics it is clear that 90 percent of cases of a tumor will have a similar structure, as well as adenocarcinoma.

Only varies the different degree of malignancy. When the tumor is located in the tail area, the neoplasm occurs much less frequently.

Fixed in practice 5-7 percent of cases with such developments. With total lesions of the gland, 20 percent of people face a tumor, which affects the body of the entire organ.

Clinical picture in the diagnosis of pathology

If the patient applied for help to the doctor in the early stages of the development of the iron of the gland, then when surrendering blood analysis, it is not always possible to note the violation of the body's work.

But for launched forms of pathologies, such changes are characteristic of the increase in the ESP indicator, and the hemoglobin may be significantly less than the norm.

Hyperbilirubinemia, hypoproteinemia, an increase in alkaline phosphatase is also observed.

Doctors converge in the opinion that the most effective analysis in this case will be the surrender of analyzes for oncomarkers.

Using carbonhydrate glycoprotein to determine the tumors. If a person is healthy, then the norm varies within 37 units. In the case of the oncology of pancreatic gland, the concentration of carbonate glycoprotein will be several times higher, sometimes not only dozens, but hundreds, thousands.

It is important to note that if the initial stage of development of oncology is observed in the body, the indicator may not go beyond the norms permissible, and therefore this method is not always relevant to use.

Sometimes, it is not needed at all, even if the patient is included in the group subject to cancer.

In recent years, scientists have succeeded a lot in this area. The high efficiency of the methodology for the detection of antigen CA 494 in the blood of people who collided with the early stages of oncology was determined.

In particular, this method is useful when you need to differentiate the pathology of a malignant nature from chronic form of pancreatitis.

Diagnostic research

One of the most affordable and justified to identify pancreatic cancer is an ultrasound study of the abdominal cavity.

Due to the qualifications of the doctor and the quality of the equipment used, the tumor can be detected if it is size for more than 2 cm.

If the diagnosis is confirmed, you need to specify the dimensions, the position of the tumor, and, as well as how much it involved in the process of organs located nearby.

The analysis is really very reliable, but very expensive. If the tumors are more than 3 cm in size, the CT will allow to determine all the above characteristics.

It is worth considering that this study is associated with a large dosage of X-ray irradiation, therefore it is not necessary to conduct it often or in those situations where without use you can do.

This study is comparable to MRI. Only there is a restrictive factors for magnetic resonance tomography.

It is impossible to conduct an examination if metal implants are in the body, under which it is worth understanding metal plates, joint prostheses, artificial heart valves and other devices that support the normal life of the body.

These methods to help determine the neoplasm allow you to clarify the location of the lesion and the tumor zone.

It will also be necessary to conduct positron-emission tomography, which is aimed at identifying the tumor and the presence of metastasis.

To this end, you need to introduce radionuclide. This substance cancer cells are actively absorbed.

During this process, snapshots are taken by a special device, helping to imprint, as the substance is distributed in the human body.

Such a study is very important with the intended operation.

It allows you to assess the amount that is necessary for surgery, and whether such additional treatments should be used as radiation or chemotherapy.

A description of the diagnostic methods of the pancreas cancer can be long for a long time, but most importantly, it is important to clarify, even at an early stage of pathology, it is important to comply with all instructions of the attending physician.

You need to trust the specialist, ask questions interested in, do not be shy to say what bothers it. Each nuance in the treatment of oncology plays a big role.

Medicine does not stand still, new methods of treatment of pathology have been developed, even if in recent times, some cases were recognized by physicians inexperienced.

All this indicates that there is a chance for recovery, you need to gain strength and faith in the best.

Medical therapy

The healing course of oncology is never easy. Already at the first stage, when the diagnosis and causes of pancreatic cancer find out, many patients face the need for palliative therapy.

These treatment methods are reduced to creating conditions for a person for good quality of life.

Oncology is dangerous, but risks increase at times, when the process of developing the tumor affects the bile canals.

This fact is dominant why there is no such symptom of pathology as jaundice. It should be concluded that treatment is started late.

The main method of therapy will be in the surgical method. But you need to admit that it is not always possible.

When running oncology stages, the operation is contraindicated, as in cases of severely general patient condition.

Treatment with a surgical way will be possible only in 5-15 percent of people. The ability to carry out the operation depends on the tumor location factor and the extent that the process has spread.

The situation is complicated by the fact that the Operation itself forces special qualifications from the surgeon. This is a very difficult operational intervention in technical terms.

It is determined by the fact that the pancreas, unlike other organs of the abdominal cavity, does not have a shell.

All this does not give the authority to join the intestine when the surgeon conducts appropriate operational manipulations.

Near the organ there is a lot of blood vessels, which provokes complications in the form of possible bleeding.

The operation will seriously hit by the patient, a person with oncology and is so exhausted. It is important to take into account the fact that when bleeding is the risk that metastasis will be even more serious in the body.

The thing is that metastases are cascading with cancer, they are spread with blood for the rest of the authorities.

It watches that the foci of oncology may appear, even away from the source of the body's infection.

Colonies of malignant cells across the gate vein fall into the cavity of the liver, after visiting the lungs. In the direction with the arterial channel, they move to other organs.

They are conducted even before operations to achieve the operable state, in other words, reduce the degree of propagation of the tumor by reducing its size.

The problem lies in the fact that there are not always cancer cells of the gland weakly resistant to the effects of chemotherapy drugs or radiation irradiation. The component of the funds comes to them with difficulty.

An increase in the dosage of drugs and the intensity of the radiation mode of MaludoMillo. The risk of increasing side effects is quite large.

The tumor gland is able to form resistance to agents of funds. The treatment of therapy is mainly to improve the appearance of the skin of the human body, by eliminating jaundice.

It is important to establish the permeability of the small intestine, a 12 -irtic intestine and bile duct.

It is necessary to reduce the severity of pain syndrome, restore the gland in the treatment of diabetes mellitus, as well as remove other side effects.

Appeal to the doctor

During the emergence of suspicion of pancreatic cancer, you need to seek help from a gastroenterologist.

After a comprehensive examination, which includes radial, endoscopic methods and some others to confirm the diagnosis, the patient will be redirected to the oncologist.

Possible complications of oncology

Currently, the cancer disease of the pancreas is considered to be among the most severe forms of oncology.

In the case of the cancer of the gland, the condition is seriously complicated by the authority itself, as well as other complications from the hepatobiliary system.

With the launched states of cancer, the neoplasm gives metastasis, which leads to a deadly outcome.

Preventive measures

In fact, accurate measures of prevention to prevent the development of pancreatic cancer has not yet been created.

The fact is that the main factor in the development of the tumor is pancreatitis. Those. From this it is worth a conclusion that you need to do everything to prevent the development of inflammation in the area of \u200b\u200bpancreatic gland.

In accordance with the data obtained from the American Cancer Community, in 2009, 42470 new cases of the diagnosis of pancreatic cancer were registered.

Of these, 35,240 cases ended with fatal. In recent years, the risk of developing pathology gradually subsides, but the expulsion of the outcome remains at the same level.

In the United States of America, the cause of the oncology of pancreatic gland is the 4th for mortality in the country.

The risk of painful pathology throughout the lifetime is 1 to 72 cases. Both women and men suffer from pathology equally. The risk may vary in view of some risk factors.

If they again turn to research, the DNA of the organs of the organ itself may affect the development of a disease.

Their disturbed formula entails the unhealthy development of the cellular system provoking the formation of tumors.

Researchers made a big breakthrough in understanding how the DNA changes make a healthy cell in the DNA cause a tumor to develop.

It was possible to understand that DNA could mutate and activate during this process oncogenes. They become the reason for disconnecting the genes of tumor suppression.

DNA faces some carcinogenic family syndromes, congenital mutations cause a very high risk of developing certain tumors, increasing the risk of the oncology of pancreatic gland.

It turned out during research that in 10 percent cases of oncology, the DNA was the cause for such an unfavorable diagnosis.

Sometimes, they have a relationship with different types of cancer tumors. The help of a doctor who disassembled in inherited oncological syndromes will be useful. After all, these cells can be adopted from their closest relatives.

conclusions

Summing up, it is worth noting that representatives of the American Cancer Community recommend to all people undergo genetic testing to understand how much the body is inclined to oncology.

There are many new surveys to detect people from a risk group.

Also, cell mutations can be acquired, and therefore it is necessary to exclude bad habits, try to lead a healthy lifestyle and maintain a normal weight, in time to treat pathology developed in the body, taking into account the competently developed technician of therapy.

Useful video

Pancreas and organ of the digestive system. In a normal developed body, it weighs no more than 85 g and is in anatomical orientation behind the stomach. The pancreas performs two functions in the body: endocrine and exocrine. When a violation of the body is happening, the body's immune system will fail, while it ceases to cope with the development of pathogenic cells, which are progressing in its development, the cancer of the gland is beginning to emerge.

In often, pancreatic cancer, has inconspicuous symptoms and manifestations of their development. In other cases, it is manifested only in recent stages, when an increased focus of cancer education, begins to spread and create failures in the work of the body.

How the tumor neoplasum grows, depends on the stage of development of the pancreatic cancer. To understand this, consider some and the main types of cancer arising in the pancreas affected iron:

1. The first stage of cancer development. At the moment of education, the tumor is located in small sections within the pancreas, without development in other areas adjacent to the pancreas.
2. Second stage of development of oncology. This pathology of the second stage is divided into two groups: 2a and 2B. Group 2a. The proliferation of the tumor occurs to neighboring authorities of the pancreas: a 12-risen intestine, choleretic ducts. At the same time, the distribution to the lymph nodes does not occur. As for the group 2B, the spread includes in addition to the listed under 2a, the lymph system of the organism is also the lymph nodes. This development allows different forms and volumes of neoplasms.
3. The third stage of the pancreatic cancer. The pancreatic cancer and its third stage of development, has significant differences from previous stages. Increased growth in the human body is complemented to the above-listed stomach, spleen, a thick intestine. Also, gradually captures the tumor of large nerve endings and blood vessels. Starting to spread from lymph nodes, the organism metastasis occurs, and the tumor goes to the liver, kidneys, the respiratory system.
4. There is also the last stage, the fourth, in which the pathology of the disease applies to the whole organism and is not subject to treatment.

The identification of this deadly disease occurs only after the development of oncology outside the body of the gland, in connection with this, the predictions of recovery are too small. Statistics show that in the pathology of cancer development, only 25% of people exceed the bar of life 5 years, and then after surgical operations and treatment. According to general indicators, if the treatment of cancer in the disease of the oncology of the pancreas is impossible without surgery, then this is a very small percentage of survival. Approximately 2% of all sick patients.

All stages of developing pancreatic cancer have and have negative consequences per person. Therefore, it is necessary, even with normal well-being, attend a medical institution and undergo the necessary diagnostic measures. These actions will allow reveal in an early stage, any health problems, pancreatic cancer, which will give a chance of timely response to problems and recovery.

What are the causes of cancer and oncological diseases of the pancreas? The main impact on the development of an oncological disease is provided by the environment of residence and lifestyle of a person. Factors of the possible appearance of a malignant tumor:

• in many cases, the development of oncological diseases of the pancreas is caused by chronic pancreatitis, a kosy, the heredity of pancreatic diseases;
• the age of the patient for 40 years, but recently the pathology has a young one that causes concerns of scientists and researchers;
• abuse smoking;
• developing diabetes;
• excess body weight (obesity);
• genetic history (heredity);
• human carcinogens (benzidine, asbestos, in naphthylamine) enter the body.

Also in the list of the main causes of development, the absence of vitamin D3, alcohol abuse, a low-tech lifestyle.

Symptoms of the appearance of cancer

Pancreas Cancer, sometimes flows without explicit signs and symptoms, which creates the conditions for its detection, when it is already late to apply certain types of treatment. After all, there are certain positive methods, but the use is allowed only at the beginning of the development of oncology.

Therefore, many are interested in what signs and symptoms will tell about the impending mortal problem? In total, the following first signs of cancer are distinguished, indicating the danger of the development of this pancreatic pathology:

1. Pain symptoms in solar plexus, in the back. Usually occurs sharply, it creates a strong pain effect, when it is tooling the legs in the knees to the thoracic human body, softens and passes.
2. Dry slimming. Strong weight loss without explicit for that causes.
3. Permanent thirst. Removing it with abundant use of liquid, respectively, there is plenty of uriction, which will also be a precursor of diabetes mellitus. Insulin addiction disease, often concomitant oncology disease.
4. Vomit urge. These symptoms are characterized by squeezing the tumor, a peculiar transition from the stomach into a 12-point intestine.
5. Hepatitis A, B, s. With this pathology, the yellowing apples, skin cover occurs. It often occurs during the oncology of the head of the pancreatic gland. In this period, there is squeezing of gallops, which provokes a developing hepatitis, accompanied by itching, due to the accumulation in the skin of bile molecules.
6. Dull pain in the right hypochondrium. When developing oncological diseases, a tumor puzzles a spleen vein, an increase in spleen (splenomegaly) arises.
7. Liquid chair (diarrhea). Calurative formations have a liquid substance and a strong smell, mostly slicer. The cause of such a smell, the insufficient number of enzymes of splitting fat components of food.
8. Insulinoma. An emerging tumor with insulin production. The main symptoms of this pathology: manifestation of trembling hands, severe weakness, fainting, hungry state, increasing heartbeat. It is possible to create conditions for the occurrence of coma. All this indicates a low glucose indicator in human blood flow.
9. Gastric (increased gastrin production). This type of disease is accompanied by a strong heartburn, an increase in acidity in the stomach, ulcers that do not pass even with complex therapy of symptoms. Gastrin provokes additional symptoms, which results in treatment to zero result.
10. Glucagon. The neoplasm produces a large amount of glucagon. With this development, there is a sharp weight loss, a strong thirst and an increase in urination. Red-brown education appears on the human body, the human language becomes bright orange. All this shows an increased amount of sugar in the blood of a patient.

Pancreatic cancer and symptoms, in often manifested in people suffering from diabetes, pancreatitis.

There are also the first symptoms of the occurrence of pancreatic cancer, thanks to which you can respond in a timely manner to this problem. True, it still depends on the place of the neoplasm and its aggressive manifestation. Pancreatic cancer and the first symptoms of the deadly disease appeared:

1. Pancreathing head cancer - the appearance of hepatitis, weight loss, pain in the abdomen, fat selection in feces.
2. Cancer of the tail part and the common body of the pancreas - weight loss, pain symptoms in the stomach.

What attentions needs to be paid is to the sequence of the first signs of the disease. First of all, cancer head of the gland is manifested, and then the body and the tail. In this case, the symptoms are called "pancreas", which is created by the development of the tumor near the gastrointestinal organs.

Symptoms on more remote stages

The pancreatic cancer at the last stage is not treated, but there is a palliative treatment, in which it is possible to extend the life and significantly alleviate the state of health. The symptoms of the extreme stage of development of the oncological disease, largely depends on the rate of propagation of pathology and location of the tumor. When development occurs towards lymphatic and nerve components, there are serious problems with the reflex of swallowing, pronunciation of proposals. Also appears veins hollow syndrome.

The developing tumor in the chest, puts pressure on the organs adjacent to pathology, which worsens the state of the patient.

The symptoms and the spread of the pathology of the last degree of pancreatic cancer depend on the propagation rate, the volume of the tumor. The difficulty of the disease is that it is not subject to signs of definition at an early stage of development, and as usual occurs, it is detected only by chance or with random diagnostics:

• constant feeling of fatigue, and with a small work of severe fatigue;
• lack of appetite;
• severe shortness of breath;
• severe weight loss;
• changing the color of the human skin on a more yellowish color is associated with the body poisoning bile;
• constant vomiting, nausea attacks.

The occasion of the pancreatic head cancer also has its own symptoms and is the most aggressive neoplasm. In pathology, 98%, patients die for 3-5 years. All wines later diagnosis of the disease. What is the reason for the occurrence of cancer in the pancreas head?

The main factors for developing an oncological tumor:

• (smoking, alcohol, drugs);
• improper power with synthetic additives;
• diseases of choleretic paths and gallbladder;
• launched form of diabetes.

As for the symptoms in the oncology of the head of the pancreas, it has such symptoms of their development at the last stage:

1. Pain syndrome in the field of solar plexus, amplifying pain in the top of the back. This is caused by the pressure of the tumor on the nervous end, overlapping the biliary tract.
2. Strong weight loss, right up to cachexia.
3. Also in the later stages, the tumor germinates in the tissue of other human organs, completely grows in the pancreas.
4. Dimming urine.
5. Cal becomes white.
6. Hepatitis on symptoms is similar to category S.
7. Skin itching, to blood.
8. Failure to work internal human organs.

As well as the symptoms that appeared during the pancreatic cancer in women, in many ways, serve as an indicator of the wrong life:

• smoking in a huge amount;
• abundant alcohol consumption;
• drug addict;
• obesity;
• excessive consumption of roast food.

Even having physiological differences, the symptoms of the disease is largely the same with men, but there will be only a difference in pain syndromes, since in some cases, nevertheless, the tumor squeezes the internal organs in a woman.

Diagnosis of pancreatic cancer

Pancreas Cancer, with early diagnostics, creates difficulties due to an indefinite clinical leakage. Rarely, about 20% of patients received a chance of diagnosing at an early stage of development, which gave the possibility of healing. Therefore, at the initial stage of diagnosing the organism on the subject of cancer, a laboratory survey is used.

Laboratory diagnostics of oncology. At the same time, a general blood test is taken, which, in the study, shows the signs of developing anemia, which corresponds to the flow of platelets, ESR. With a biochemical survey of blood, in pathology, it is detected by bilirubinemia, increased activation of phosphatases, the abundance of hepatic enzymes, indicates the devastating effect on the ducts of choleretic channels or decomposition of the hepatic tumor tumor. In the blood, signs of mallabsorption are also found.

Pancreas, a vital organ of man, and cancer brings strong changes to her work, which in the end in pathology, threatens with a fatal outcome.

Cancer Detection Methods

Pancreatic cancer is also determined using the detection tool method:

1. Endoscopic ultrasonography. First of all examine and exclude the diseases of the gallbladder and the pathology of the liver, which makes it possible to determine the pancreatic tumor. The study conducts a biopsy selection for a further study of the human body.
2. And, makes it possible to view visually the state of the tissue of the pancreas and reveal the neoplasms and the size of the tumor, lymphatic nodes.
3. PET reveals the location of neoplasms (metastasis) and helps to detect pathogenic cancer cells.
4. Laparoscopy is a diagnostic event, reveals metastases in the liver, intestines or peritoneum.

At the first signs or suspicions on the oncology of the pancreas, urgently undergo a comprehensive examination at the attending doctor.

Localization location

The pancreatic cancer in the main mass of manifestations, in diagnostic data indicators, occurs in the head of the pancreas. This type of pathology is developing in 70-80% of the affected appeals. In the body metastasis of the gland, 10-15%. In other cases, the tail of the pancreas takes itself.

The appearance of a tumor during the oncology of the pancreas:

• lymphogenic;
• hematogenic;
• implantation.

The lymphogenic tumor passes in stages.

1. stage. Pancreatoododenal lymph nodes (appearance in the head of the pancreatic human head).
2. stage. Retropyllic lymph nodes.
3. stage. Curl and top-drying knots.
4. stage. Retroperitoneal lymph nodes.

At the time of hematogenous development of cancer pathology, they are found in the liver, kidneys, patient bones.

Implantation oncological tumor - the transfer of cancer and pathogenic cells throughout the human peritoneum (web).

Cancer - the disease of the pancreas, in their mortality, is in second place after AIDS and HIV. Pathology requires response to the symptoms of the disease, which is capable of extending and preserving a person's life.

Pancreatic cancer is an aggressive shape of cancer with a disappointing forecast - it quickly applies and is accompanied by strong pains in the later stages, and cancer cells penetrate other organs. At the same time, the digestive enzymes can fall from the pancreas in the surrounding tissues, which leads to their inflammation and destruction. However, at relatively early stages, pancreatic cancer is accompanied by a small number of symptoms, or they are absent at all. Thus, this disease is difficult to diagnose, so it is necessary to closely monitor possible signs in the digestive system and the abdominal cavity. Early diagnosis leaves more opportunities for treating and surgical intervention.

Steps

Part 1

Identify early symptoms of pancreatic cancer

Take care of the yellowing of the skin and eyes. One of the first signs of the pancreas cancer is jaundice, that is, the yellowing of the skin, eye and mucous membrane due to the high content of bilirubin in the blood. Although jaundice is more often associated with liver diseases, pancreatic cancer often causes the edema of the liver and the gallbladder, which violates the proper work of these neighboring organs. Inspect your skin and eyes with good lighting in the mirror and check if they are not the wishes.

• Jaundice also causes skin itching, so pay attention to this sign.
• Yellow eye proteins (sclera), and not a rainbow sheath, which saves its familiar gray, blue or green.
• If the yellowing of the skin is weakly noticeable, to detect the jaundice, the doctor can check the content of bile in the urine or assign the blood test.

1. Pay attention to the stomach pain. One of the early signs of the pancreatic cancer can be scattered pain and a new feeling in the abdomen, although many patients in the early stages do not have any pain. Pancreas is located behind the stomach, approximately in the middle of the abdomen. It produces hormones, digestive enzymes and insulin, which controls blood sugar content. If the new stomach pain does not pass during the week, consult a doctor.

   • A small or average pancreatic tumor is difficult to determine by palpation (deep tackling), and this method is practically useless, since this iron is located in the depth of the abdominal cavity and is surrounded by other internal organs. In addition, pancreatic cancer often causes edema of the liver and gallbladder, which is easier to detect when palpation, which can lead to an incorrect diagnosis of liver cirrhosis or cholecystitis.
   • Due to the increased sensitivity of the abdomen, fatigue and diarrhea of \u200b\u200bpancreatic cancer in the early stages, it is possible to confuse with infection, ulcerative colitis, crown disease or irritable intestinal syndrome.

2. Pay attention to fatigue and weakness. Another early sign of the pancreas cancer, as well as most of the other forms of cancer, is an increased fatigue, a sense of fatigue and weakness. This is explained by the fact that the pancreatic cancer can lead to blocking the flow of digestive fluids, and also by the fact that cancer cells absorb many resources, the large amount of energy burned and overload the immune system. Therefore, in the early stages, cancer can resemble a viral infection, but without a cough characteristic of her, Chihannia, a cold and the like.

   • In the early stages of pancreatic cancer, patients often experience unless fatigue in the evenings, they lose the desire to play sports and even leave the house.
   • Increased fatigue and fatigue in pancreatic cancer usually do not pass after a long sleep.
   • Since, as muscle cancer develops, they cease to receive enough nutrients (glucose) and energy, they weaken, can even appear trembling.

3. Pay attention to the increased sugar content (glucose) in the blood. One of the main functions of the pancreas is the production of insulin hormone, which delivers glucose from the blood into the cells of the body, where it is used as a source of energy. In disruption of the pancreas, the sugar remains in the blood due to cancer, and its concentration is increasing there. Too high level of glucose in the blood causes lethargy, feeling of fatigue, thirst, weakness, irritability, more frequent headaches.

   Pay attention to chronic diarrhea or too light chair. Another possible sign of pancreatic cancer in the early stages is chronic diarrhea. In addition, clay-like or abnormally light chair serves as a sign of insufficient quantity of bile. Diarrhea for the pancreatic cancer is explained by the fact that there is not enough digestive enzymes in the small intestine - this prevents the normal digestion and absorption of nutrients. Consult your doctor if the diarrhea attack lasts longer than one week.

   • Another sign that the pancreas does not function as needed and does not produce (or does not allocate) a sufficient amount of fracturing enzyme fat (bile) is a fatty chair with a more unpleasant smell than usually, which often floats over the water.

   Part 2

   Symptoms of pancreatic cancer at later stages

   1. Pay attention to burning abdominal pain. As cancer develops, his symptoms are pretty quickly becoming more noticeable. One of the first expressly pronounced symptoms is a moderate or strong scattered pain in the abdomen, which often carries a burning or corrosive character. The pain can also be given to the middle area of \u200b\u200bthe back (thoracic spine). Most patients with pancreatic cancer are first addressed to the doctor precisely because of this severe pain.

      Pay attention to strong nausea and vomiting. Another symptom of pancreatic cancer at later stages are moderate or strong nausea and chronic vomiting. Nausea is practically not stopped, it increases, it subsides throughout the day, and vomiting may happen one, and sometimes several times a day. At the later stages of the pancreatic cancer, it becomes very difficult to eat, often the body refuses to hold the drinking liquid.

      • The cause of nausea and vomiting are severe pain and constant discharge of adrenaline and other stress hormones.
      • Chronic vomiting can quickly lead to dehydration of the body and the shortage of electrolytes (mineral salts), which can cause strong muscle spasms and rapid heartbeat.

   2. Pay attention to the unexpected weight loss. With the pancreatic cancer weight loss can be caused by many factors. As a rule, cancer causes the exhaustion of the body (cachexia), since cancer cells burn a large amount of energy. In addition, pain in the stomach, nausea, and sometimes vomiting make it difficult to eat, which also leads to weight loss. If you lose considerable weight (as a rule, it first becomes noticeable by the face and coverage of the waist), immediately consult a doctor so that he checked the state of your health.

      • Even if you can eat and digest food, it is difficult for your body to absorb nutrients, since the pancreas produces an insufficient number of digestive enzymes.
      • For this reason, patients with pancreatic cancer often recommend taking nutritional supplements with enzymes that contribute to digestion and help maintain normal body weight.

   Part 3.

   Medical diagnosis

   1. Pass the appropriate blood test. Most likely, with some or all the symptoms listed above, your doctor or oncologist (specialist in cancer) will appoint you several blood tests. Some blood tests make it possible to identify pancreatic cancer and exclude other possible causes of observed symptoms. Such analyzes include clinical (deployed) blood test, liver functional tests, serum bilirubin, kidney functional test and search for various tumor markers.

      • Tumor markers (oncomarcresters) are substances that are sometimes detected in the blood of cancer patients. Two of them are evidenced by the pancreatic cancer, which are called Ca 19-9 (carbohydrate antigen 19-9) and cancer-embryonic antigen (REA).
      • Increased level of these tumor markers is detected not in all patients with pancreatic cancer. In addition, their level can be enhanced for other reasons, so this is not a unambiguous criterion. Nevertheless, this simple and non-invasive analysis helps to determine whether it is worth further examination.
      • It is often helping to determine the level of hormones (such as chromograin A, C-peptide and serotonin), since in patients with pancreatic cancer their level is often increased.

   2. Complete all the necessary medical tests with visualization. If, on the basis of the symptoms described by you and the blood tests, the oncologist will suspect that you have a pancreatic cancer, it can assign a number of tests with visualization. It can be a computed tomography (CT) and / or magnetic resonance imaging (MRI) of the abdominal cavity, endosonography of the pancreas and retrograde cholangiopancratography (RHPG). If these tests confirm the cancer disease, you will be prescribed more detailed research to determine whether the tumor is distributed - this methodology is called the definition of the cancer stage.

   3. Think about biopsy to confirm the diagnosis. If different analyzes and tests indicate a pancreatic cancer, in order to fully confirm this diagnosis and determine which cells are most affected, the doctor will prescribe a biopsy for which a sample of pancreatic tissue is taken. The sample of the pancreas fabric is taken under anesthesia, and this can be done by three methods: with the help of a needle, an endoscope, or surgically.

      • With a perkatal biopsy (it is also called a thin-game aspiration puncture biopsy) through the skin of the abdomen, a long thin hollow needle is introduced, with which a small sample of fabric (tumors) is taken from the pancreas.
      • With endoscopic biopsy through the esophagus, the stomach and the small intestine introduced an endoscope, with the help of which the sample of the fabric is cut from the pancreas.
      • Surgical biopsy is the most invasive method that implies the incision of the abdominal cavity. A laparoscope is inserted into the incision, with which the doctor takes a fabric sample and examines the insides to find out if the tumor spread to neighboring organs.

To date, oncological diseases are the most deadly. Moreover, in most cases, the disease could be stopped if the symptoms were read and understood. But for obvious reasons, people ignore the seemingly insignificant discomfort, do not go to the examination, and when they feel pain. And when symptoms are becoming too obvious, it is no longer possible to help the patient.

Among the most common cancer tumors, the sixth place occupies the damage to the pancreas. Moreover, detect it at an early stage, it is rare quite rare. Today we want to talk about what are in the early stages. Perhaps for someone it will be a chance to seek help.

general description

It is very important to have an idea of \u200b\u200bwhat is the authority. The main functions are digestion and mining of hormones. We all know from childhood where we have a heart and stomach. However, this tiny iron may be in some plane even more important.

The digestive function is the development of digestive enzymes, that is, special substances, with which proteins, fats and carbohydrates are cleavage. Without this, food is simply not learned. In addition, iron is engaged in the development of hormones that are responsible for metabolic processes. This is insulin and glucagon, and still a whole complex of substances responsible for the production of gastric juice.

The symptoms of pancreatic cancer in the early stages are most often reduced to typical manifestations of pancreatitis. That is, a person has discomfort after meals, takes painkillers or enzymes and soothes on it. The disease progresses and as a result becomes already inoperable. Now the doctor, based on the body's condition, can offer chemistry or radiation therapy. This is not a treatment, but the means to stop the growth of the tumor.

The reasons

In fact, the doctors continue to guess why the human body is beginning to develop cancer cells to develop rapidly. What is it? This is not an alien organism, not bacterium or virus, which is why such difficulties in treatment arise. Cancer is the cells of your body under the influence of various factors. Typically, cells are divided only to replace the wear or dying precursors. But in the cancer cell, DNA is changed, it will share uncontrollably, and being immortal. And the cells created also do not die as their function is performed.

In fact, one task remains: grow and multiply. As a result, the tumor fills one organ and penetrates the second, changing its structure. Moreover, such cells cannot perform the function initially embedded in them. As a result, skipping the symptoms of pancreatic cancer in the early stages, the person is slow, but correctly goes to the destruction of the entire process of digestion. The rebirth authority is not able to produce the necessary enzymes and hormones.

Why cancer cells affects pancreas

We will not consider all the reasons for the development of oncological diseases, because they are too much. Let us dwell only on those (according to doctors) lead to the development of a cancer in the pancreas.

Cancer varieties

The symptoms of pancreatic cancer in the early stages will be highly dependent on how the disease begins. There are many species, and only the attending physician can understand this. Based on the characteristics of the anatomical concentration of the tumor, the main types are determined:

• Cancer head head.
• Body.
• Tail.

Based on this, the doctor can already make certain forecasts. However, in addition, the surgeon necessarily takes the analysis of histology. Now he will be able to determine the specific type of cells from which cancer developed. So in the medical book appear "adenocarcinoma", "insulinoma", "gastrone" and others.

Alarm signs

In order to appeal to the doctor and stop the development of the disease, it is very important to notice the symptoms of the pancreatic cancer in the early stages. Diagnostics usually occurs much later when the metastases have penetrated the lymph nodes. Therefore, each of us needs to be very carefully related to your health. If something bothers, you need to go through a thorough examination, and not to let everything on samonek.

So what are the symptoms of pancreatic cancer in the early stages? Signs of ominous diagnosis are still very weak, but the first call is pain. It is localized in the upper half of the abdomen, under the stomach. Frequently gives back and can wear a look. With the increasing tumor, symptoms can only increase, so it is not worth pulling. Characteristically enhancing pain when tilting forward. In parallel, thirst can increase and it is often possible to observe the diarrhea. Chair in this case is liquid and fetid.

Cannot ignore

How often regret come to man too late. When there are already 3 or 4 stage in the card, so you want to turn everything back. Then the person would not have missed the symptoms of pancreatic cancer in the early stages. The first manifestations, in addition to painful syndrome, are connected with weight loss. Slimming is associated with impaired fat absorption as a result of an insufficient secretory function of the pancreas. If you note that you started to lose weight without visible reasons, it means that you need to immediately contact the clinic and pass the tests.

Laboratory diagnostics

What methods will help confirm or disprove the symptoms of pancreatic cancer in the early stages? Uzi is the very first tool that will allow you to find changes in tissues, however, usually patients pass this procedure in the later stages, to clarify the localization of the tumor, and not for its diagnosis.

First of all, you need to hand over a detailed blood test. With oncological diseases, hemoglobin falls most often and ESP grows. If the doctor sees such changes, then without hesitation, it is limited to an oncologist for further examination.

Final diagnosis

Only when a person falls into the oncology, he can pass a full examination. Here specialists are able to diagnose tumor processes. In the early stages, even the UAC works very well, it shows typical changes. Biochemistry shows bilirubinemia, as well as hepatic enzymes. Oncologist defines oncomarcres, which show the nerve of the tumor. In the early stages, markers are not detected.

Depending on the localization of cancer

How can the symptoms of the pancreas cancer can change in the early stages? Forecasts with timely identification of causes are very favorable. The percentage of survival is 96%. Of course, then it will have to undergo a supporting treatment, but this is not the most bad development of events.

If the tumor is localized in the head area, most often patients marked jaundice and skin itching, a change in urine color. It is with such an arrangement of the tumor that anorexia is most often observed, vomiting when trying to eat. The more the neoplasm is growing, the stronger it squeezes the duodenum and the lumen of the stomach.

Localization in the body or tail can be marked with episodes of bleeding. The clinical picture can resemble sharp cholecystitis and pancreatitis. In later stages, the intestinal obstruction is possible, since the intestinal lumen is narrowed.

Degree of disease

Before appointing treatment, the doctor will definitely find out the degree of proliferation of the tumor and on the basis of this will diagnose. The most favorable forecasts at the first stage. The size of the tumor is still small, it does not go beyond the limits of the gland and amazes only one of her department (head, body or tail).

The second stage involves the spread of a tumor to organs that are located nearby. These are biliary ducts or duodenal gut. This is option 2a. The form 2B implies the spread of the tumor to the nearest lymph nodes.

The third stage is already very serious. The tumor is striking the stomach and spleen, a fat intestine, selected to large vessels and nerves. In the fourth stage, the process of metastasis for all organs and systems begins.

We told you the basic symptoms of pancreatic cancer in the early stages and the degrees that are determined by its localization in the body. Now briefly note the possibilities of medical intervention in this process.

Treatment

Depends on the timeliness of the appeal. If you managed to identify the symptoms of pancreatic cancer in the early stages, the treatment will be as efficient as possible. In this case, the doctor chooses from three options:

• Surgical intervention.
• Chemotherapy.
• Radiotherapy.

In the early stages, the removal of the tumor and subsequent chemotherapy is best. But when it spreads to the surrounding authorities, the doctor is most likely not to operate the patient, because it is impossible to cut everything. It remains to be hoped only that after the course of chemistry, the tumor will decrease to such sizes, which will become commonplace.

Malignant processes in the pancreas are in third place in the "ranking" of all cancer formations of the gastrointestinal tract. Ahead of them in terms of the frequency of development only cancer of the stomach and rectum. Mortality from tumors of the pancreas in men is in fourth place among other reasons, and in women in the fifth.

Symptoms and manifestation of this disease in the United States of America are detected annually in almost thirty thousand new patients. For the nineties of the last century, its frequency in the countries of the European and North American continent has increased almost twice in comparison with the thirtiends.

In our country, the manifestation of pancreatic cancer is about 8.5 cases for every 100 thousand population. Therefore, everyone is very important to know what the first symptoms of this disease can be, as it is manifested in the future and how can you fight with it.

Symptoms of the appearance of pancreatic cancer

Clinical manifestations of this serious disease are determined by the size of the neoplasm, as well as the location of its localization. When the gland head cancer at an early stage, the symptoms are almost invisible and reduced only to common disorders.

A person feels weakness, gravity in the abdomen, disorders of digestion. Sometimes diarrhea can develop, which suggests that the exemplary function of the gland is broken.

Among the first signs of cancer, the following symptoms can be called:

• pain in the top of the abdomen;
• reducing body weight;
• numerous thrombosis;
• increase in the size of the liver;
• violation of the functional activity of the pancreas;
• exterior, no appetite, nausea.

In some cases, the first obvious sign of this terrible disease, especially in people aged, is a sharp attack of pancreatitis without visible reasons.

Symptoms of pancreatic cancer on more distant stages

After a while, such symptoms of this disease are observed, as permanent stupid abdominal pain, which are localized in the right hypochondrium or in the epigastric area. Sometimes such pains can respond in the back, lower back, or to be a squeezing nature (more often it happens when the tumor germinates in the ventilating nerve).

About 20% of patients with typical forms of cancerous disease have clinical signs for the first time detected diabetes, which are confirmed by laboratory studies. All named symptoms of pancreatic cancer do not relate to strictly specific and may be mistaken for the symptoms of the osteochondrosis of the spine or chronic pancreatitis.

In many people, very often the only symptom of the tumor in the area of \u200b\u200bthe pancreas head can be a mechanical jaundice, which develops without an accurate pain in the abdomen. Gradually, the jaundice progresses and the strong skin itching joins it and all these are signs of pancreatic cancer.

In patients with common types of pancreatic cancer, there may be signs of intestinal obstruction, the cause of which is the compression of the vertical (and sometimes lower-dimensional) duodenum segment.

The neoplasms in the body or tail of the gland are usually detected already in the later stages when strong pain in the back or epigastric area appears.

Up to this point, they do not have clinical manifestations. Pains become much more intense if the patient lies on the back, and in the sitting position or when flexing forward weaken.

If the tumor begins to squeeze the spleen vein, it begins its thrombosis, which is manifested by splenomegaly. Sometimes in the pancreatic cancer due to the development of regional portal hypertension, there is a varicose expansion of esophageal vessels and hemorrhage during their ruptures.

Diagnosis of pancreatic cancer

When conducting an objective examination, approximately 35% of patients with a diagnosis of "pancreatic head cancer" is detected by hepatomegaly, and the bottom of the gallbladder is palpable. When developing a mechanical jaundice, there is a symptom of Couvia. If ascite becomes a sign of cancer, this suggests that the tumor process is already very common and the radical operation is impossible.

When cancer, localized in the distal gland, the results of an objective study give little information, a tumor, as well as tumor infiltrate, can only be palpation with a very started process. Ascites and splenomegaly are also found in the later stages.

In the early forms of pancreatic cancer, ordinary blood tests, as a rule, do not show any deviations. In the later stages there may be an increase in ESP and moderate anemia.

In biochemical blood samples, hypoalbuminuria and hypoproteinemia are usually detected, and in the presence of mechanical jaundice - hyperbilirubinemia. Alkaline phosphatases and transaminases also increases, and the increase in phosphatase concentration is observed to a greater extent.

Significantly more information in the diagnosis of malignant neoplasms is the determination of tumor markers content. One of the most specific and sensitive markers at a given form of cancer is the carbonichydrate glycoprotein of embryonic nature. In addition, the doctor draws attention to.

In healthy people, his level in the blood does not reach more than 37 units, and in the pancreatic cancer, its concentration increases in tens of times (and sometimes hundreds and thousands).

But in the early stages of cancer, the CA-19-9 content is usually within the normal range, therefore this method has significant restrictions on screening research for the detection of the first signs of cancer, even if the patients are included in the risk group.

In recent years, information has appeared on the high efficiency of the methodology for the detection of antigen CA 494 in the blood for the early formulation of the diagnosis of "pancreatic cancer", especially if it is necessary to differentiate it from chronic pancreatitis.

Tool methods for detection of pancreatic cancer

These methods occupy the main place in the diagnosis of pancreatic tumors.

X-ray with the use of contrasting the stomach and duodenum helps to detect only some indirect signs of cancer arising when squeezed by a tumor of neighboring organs:

1. deformation of the stomach and shifting it forward;
2. deploying and shift "horseshoes" of the duodenum;
3. squeezing downward branch duodenal and the occurrence of defect defect in the inner edge.

With a large tumor sizes, X-ray examination can show a shift of small curvature of the stomach and thickening of the folds of the mucous membrane with infiltration in this area.

You can also see the squeezing and shift of the turntable in the place of the trout bundle. But all these features found are symptoms of cancer in the late stage. X-ray rays make it possible to see also narrowing the duodenum.

More informative instrumental methods of research are magneto-resonance and computed tomography, as well as ultrasound. Moreover, tomography is a more sensitive technique than ultrasound.

In order to confirm the diagnosis made by X-ray, make a puncture tumor tumor with additional control using an ultrasound or computed tomography. At the same time, most patients with cancer (90-95%) is a diagnosis of morphological confirmation.

Pancreatic Cancer Localization Place

In practice, 80% of patients with neoplasm in the pancreas are located in the body head and much less often in the tail or in the body of the gland.

It is very rare to detect the multicenter position of the tumor, as well as the diffuse form of cancer covering the entire gland completely. Usually, the tumor begins to develop from tissues of outputting ducts and in its structure represents adenocarcin with different degrees of differentiation. Sometimes, during morphological examination, an acinar adenocarcine is determined (tumor growing from acinar cells) or a flat-belling cancer.

The most often pancreatic cancer gives metastases into lymph nodes for peritoneum or nodes that are in the hepatic duodenal bond. Through the blood metastases penetrate the liver, kidneys, lungs, bones, adrenal glands and lead to violation of all these organs.