Angiovitis side effects. B vitamins during pregnancy: why is Angiovit needed?

While waiting for a baby, the female body needs support. It is necessary not only for expectant mother, but also for the proper development of the fetus. The vitamin complex Angiovit during pregnancy is an excellent helper for a woman and her baby.


The purpose of Angiovit is to replenish the body’s reserves of B vitamins. It is also used as a preventive and medicinal agent in the treatment of diseases of the cardiovascular system (heart attacks, strokes, angina pectoris, etc.), and reduces the risk of developing coronary disease, the occurrence of thrombosis and atherosclerosis. The drug normalizes homocysteine ​​levels.

Composition of Angiovit

Release form of the drug: film-coated tablets. During clinical studies, it was found that Angiovit is accepted by the body without negative consequences. Rare cases of local reactions expressing allergic rashes on the skin have been recorded. They disappear immediately after stopping this medication. No cases of overdose were identified.

Despite the obvious benefits of the vitamin complex, its use should only be started as prescribed by a doctor. Self-consumption can lead to internal imbalances in the body..

Why is Angiovit prescribed during pregnancy? This drug includes B vitamins, which is why it is prescribed for a deficiency of these microelements. They are extremely necessary at this time:


  • Folic acid is involved in the formation of nerve tissue in a child. It is also involved in the metabolic processes of nucleic acids, which are the basis of genes.
  • Pyridoxine affects cellular metabolic processes. It accelerates the body's redox reactions.
  • Cyanocobalamin is also involved in genetic synthesis and regulates the normal development of the central nervous system in the fetus. In addition, vitamin B12 acts as an antioxidant.

The use of the drug is allowed in any trimester. Angiovit is also recommended when planning pregnancy. In this case, the likelihood of pregnancy increases, and the risk of developing congenital pathologies nervous system decreases.

Angiovitis prevents the development of fetoplacental insufficiency. The condition of FPN is dangerous: it can lead to a lack of oxygen in the baby’s blood, hypoxia and the threat of miscarriage.

An obstetrician-gynecologist can prescribe Angiovit to compensate for the lack of B vitamins if a pregnant woman has diseases digestive system and kidney problems. To summarize, we can say that taking these multivitamins helps restore fetoplacental blood circulation, prevents the occurrence of anemia, reduces the risk of fetal freezing in the womb and has a preventive effect aimed at preventing mental and physiological pathologies of the baby.

Taking medication during breastfeeding acceptable in certain cases, but not recommended due to the presence of folic acid in milk.

Instructions for use of the medicine

Instructions for using Angiovit when planning pregnancy and during it do not differ much. For women, the Angiovit vitamin complex is prescribed one tablet twice a day. Taking it is in no way connected with meals, i.e. you can take vitamins before, after or during meals.

After a certain period of time, the observing doctor conducts research to identify changes in the quantitative content of homocysteine ​​in the expectant mother. When homocysteine ​​levels are normalized, the daily dose of Angiovit can be reduced to one tablet.

The drug has no contraindications for use during pregnancy. There may be rare cases of individual intolerance to the medication, as well as allergies in the form of skin rash, hives or swelling.

Angiovitis: reviews

Here's what reviews say about Angiovitis, who took it when planning pregnancy, during it and after it:

Albina, 31 years old:

I had three missed pregnancies. When I became pregnant for the fourth time, I decided that I had to make every effort to preserve and bear my child. I passed a bunch of additional tests and studies. The geneticist revealed an increase in homocysteine ​​levels. For me it was 15.6 when the norm is 15. I prescribed Angiovita in combination with iodomarin and acetylsalicylic acid (they thin the blood). The pregnancy went well, without complications. Now we are 2 months old, my son and I feel good. Thanks to Angiovit and my doctors.

Tamara, 22 years old:

The gynecologist prescribed me Angiovitis at the thirteenth week of pregnancy. The test results showed a low level of hemoglobin and the doctor recommended trying this particular vitamin complex. Personally, the drug helped me. Within two weeks, hemoglobin returned to normal. I decided not to stop and took the course to the end, because these are vitamins that are also important for the baby’s health. I myself began to feel much more cheerful. I heard that Angiovit is good for toxicosis.

Elena, 27 years old:

This complex of vitamins was prescribed to me during a difficult period in my life. After a premature birth, one of my sons was in intensive care, and his twin sister did not survive. My body was exhausted, I didn’t understand what was happening to me: my heart was beating fast, my vision was blurry, my head was constantly spinning. Yours emotional state I won’t describe it - it’s a complete collapse. In my family, many suffered from heart disease, there were cases of heart attack, so the doctor prescribed me Angiovit. I took the pills for 30 days, and after this time, I began to notice an improvement. It became easier for me to breathe, my sleep normalized a little, and the nightmares went away. I repeated the thirty-day course. Its indicators were the normalization of heart rate, the appearance of appetite and clarity in the head. Now I’m taking the third course, this time limited to twenty days. I feel like my vitality has returned to me. My son and I are enjoying life again. I believe that the effect of the drug is quite strong, so I recommend its use only after consultation with a specialist.

How to eat properly so as not to take artificial vitamins? Experienced mothers share their experiences in the video:

Increased levels of homocysteine ​​in the blood or hyperhomocysteinemia is a condition that is recorded in 60-70 percent of patients suffering from cardiovascular diseases.

Hyperhomocysteinemia occurs due to a deficiency of folic acid and vitamins B12 and B6.

The danger of this condition is that it can lead to arterial thrombosis and atherosclerosis, including diabetic vascular damage, ischemic stroke, and myocardial infarction.

There are cases where hyperhomocysteinemia took part in the formation of congenital pathology of the fetus and chronic miscarriage.

Scientists have also established a relationship between hyperhomocysteinemia and the appearance of depressive conditions, Alzheimer's disease, and senile dementia.

To minimize the likelihood of developing these diseases, it is necessary to take special vitamin complexes, such as Angiovit.

This drug is intended for the treatment and prevention of cardiovascular diseases that arise due to elevated levels of homocysteine.

Indications for use

The drug is intended for long-term prevention and treatment of cardiovascular diseases, namely:

  • angina pectoris of functional classes II-III;
  • damage to the diabetic vascular system;
  • sclerotic cerebrovascular accident;
  • ischemic stroke.

It is also worth emphasizing that the drug is used to normalize fetoplacental blood circulation (exchange of blood masses between mother and fetus during intrauterine development).

Mode of application

The vitamin complex Angiovit is intended for oral use (orally). The tablets are taken after or before meals, with plenty of liquid.

The manufacturer emphasizes that the shell must remain intact. Chewing or crushing tablets can reduce the pharmacological effect of the drug to nothing.

According to the instructions, you need to take Angiovit once a day. It is advisable to do this after waking up to protect the body for the whole day. Doctors note that when high levels methionine and homocysteine ​​therapy can be started with two tablets.

The duration of treatment is determined by a specialist separately for each patient. Usually it is 20-30 days, depending on the patient’s condition and individual indications.

Release form, composition

Angiovitis is sold in the form of white, two-layer (visible on the section) biconvex film-coated tablets.

Vitamins are placed in cell packaging of 10 pieces or in polymer jars of 60 pieces.

One cardboard package contains six contour blisters or one polymer jar.

One Angiovita tablet contains:

  • 6 mg vitamin B12 (cyanocobalamin);
  • 5 mg vitamin B9 (folic acid);
  • 4 mg vitamin B6 (pyridoxine hydrochloride);
  • as an additional component - glucose.

Interaction with other drugs

Folic acid (B9), which is part of Angiovit, reduces the effectiveness of Phenytoin (an antiarrhythmic and antiepileptic drug), which requires an increase in its daily dose. Consult your doctor or qualified pharmacist for specific instructions.

Antacids of magnesium and aluminum (antiulcer pharmacological group), sulfonamines, cholestyramine reduce the absorption of the vitamin complex, which leads to weakening useful action drug.

Pyridoxine hydrochloride enhances the effect of thiazide diuretics (the number of urination increases, decreases specific gravity urine) and weakens the activity of Levadopa (an antiparkinsonian drug that acts on dopaminergic and adrenergic receptors of the central nervous system).

Also, you should not take Angiovit together with Pyrimethamine, Triamterene or Methotrexate.

The following drugs help weaken the effects of vitamin B6:

  • penicillamine;
  • estrogen-containing contraceptives;
  • isonicotine hydrazide;
  • cycloserine.

It is worth mentioning separately that pyridoxine causes increased formation of myocardial contractile proteins. With the simultaneous administration of Angiovit and cardiac glycosides, this manifests itself in the fact that the heart muscle becomes more resistant to hypoxia.

Taking Cyanocobalamin and Thiamine together increases the risk of developing undesirable manifestations and allergic reactions.

Antiepileptic drugs, aminoglycoside antibiotics, potassium preparations, colchicine and salicylates help reduce the gastric absorption of Cyanocobalamin.

It is prohibited to combine Angiovitis with taking medications that affect the blood coagulation system. The interaction of these drugs can lead to thrombosis of small arteries, congestion and increased blood viscosity.

Side effects

Vitamins are usually well tolerated by the body, especially in autumn, spring and summer, when they are deficient. However, in some cases, allergic reactions of a local/general nature (urticaria, angioedema, itching) and other undesirable manifestations (dizziness, headaches, signs of sleep cycle disturbances, increased sensitivity of the skin) are observed.

Dyspeptic symptoms (belching, nausea, epigastric pain, vomiting, flatulence) after intensive courses of therapy are also described.

Overdose

No cases of drug overdose were found. But it should be remembered that uncontrolled use of the vitamin complex can cause symptoms of hypervitaminosis:

  • thrombosis of small vessels, anaphylactic shock (excess of vitamin B12);
  • prolonged cramps, usually in the calf muscles (hypervitaminosis B9);
  • partial numbness of the limbs, impaired fine motor skills of the upper limbs (increased concentration of vitamin B6).

It is forbidden to take Angiovit if you have hypersensitivity or individual intolerance to the components of the drug or their complex use.

During pregnancy

Taking B vitamins during pregnancy helps to avoid hypovitaminosis and prevent the development of severe fetal pathologies, namely:

  • heart defects;
  • weaknesses immune system;
  • physical underdevelopment of the vascular system;
  • retardation in physical and mental development.

Separately, it should be noted that the vitamin complex has a positive effect on the development of the child’s peripheral and central nervous system, the formation of germ layers and their physiological development during intrauterine ontogenesis.

Storage conditions and periods

Price

Patients living on Russian territory, can purchase Angiovit at a price of 200 to 250 rubles. for 1 package.

Residents of Ukraine a vitamin complex costs about 200 hryvnia.

Analogs

If necessary, Angiovit can be replaced with the drug Triovit Cardio, but this can only be done with the permission of a specialist.

Angiovit is a complex drug belonging to the category of vitamins that supports the normal functioning of the heart and blood vessels by reducing the level of homocysteine.

The drug is prescribed as an adjuvant to patients suffering from pathologies of the vascular network, as well as a violation of the integrity of the walls of blood vessels.

In this article we will look at why doctors prescribe Angiovit, including instructions for use, analogues and prices for this drug in pharmacies. Real REVIEWS of people who have already used Angiovit can be read in the comments.

Composition and release form

The vitamin complex Angiovit is produced in film-coated tablets (10 pieces in blister packs, 6 packs in a cardboard box).

Each tablet contains:

  • cyanocobalamin (vitamin B12) – 6 mcg;
  • folic acid (vitamin B9) – 5 mg;
  • pyridoxine hydrochloride (vitamin B6) – 4 mg;
  • glucose (is an additional component).

Clinical and pharmacological group: B complex vitamins.

Why is Angiovit prescribed?

The drug is intended for long-term prevention and treatment of cardiovascular diseases, namely:

  • angina pectoris of functional classes II-III;
  • damage to the diabetic vascular system;
  • sclerotic cerebrovascular accident;
  • ischemic heart disease;
  • myocardial infarction;
  • ischemic stroke.

It is also worth emphasizing that the drug is used to normalize fetoplacental blood circulation (exchange of blood masses between mother and fetus during intrauterine development).


pharmachologic effect

Angiovit is a complex preparation containing B vitamins. It has the ability to activate key enzymes of methionine transsulfuration and remethylation in the body - methylenetetrahydrofolate reductase and cystathione-B synthetase, resulting in an acceleration of methionine metabolism and a decrease in the concentration of hymocysteine ​​in the blood.

Hyperhomocysteinemia is an important risk factor for the development of atherosclerosis and arterial thrombosis, as well as myocardial infarction, ischemic stroke, and diabetic angiopathy. The occurrence of hyperhomocysteinemia is promoted by a deficiency of folic acid and vitamins B6 and B12 in the body.

Instructions for use

According to the instructions for use, Angiovit is taken 1 tablet per day, regardless of food intake, for 20 days or a month.

Contraindications

The drug is generally very well tolerated by all groups of patients. This explains the almost complete absence of contraindications to its use, with the exception of individual intolerance to the components included in the complex.

Side effects

The use of Angiovit can cause allergic reactions, headaches and nausea.

Analogues of Angiovit

Among the analogues of Angiovit, the following complex vitamin preparations should be highlighted:

  • Alvitil;
  • Aerovit;
  • Benfolipen;
  • Vetoron;
  • Vitabex;
  • Vitamult;
  • Gendevit;
  • Kaltsevita;
  • Makrovit;
  • Neuromultivitis;
  • Pentovit;
  • Pikovit;
  • Rikavit;
  • Tetravit;
  • Foliber;
  • Unigamma.

Attention: the use of analogues must be agreed with the attending physician.

Vitamin B complex

Active ingredients

Release form, composition and packaging

60 pcs. - contour cellular packaging (1) - cardboard packs.

pharmachologic effect

Angiovit is a complex preparation containing B vitamins. It has the ability to activate key enzymes of transsulfuration and remethylation and cystathione-B-synthetase in the body, resulting in an acceleration of methionine metabolism and a decrease in the concentration of hymocysteine ​​in the blood.

Hyperhomocysteinemia is an important risk factor for the development of atherosclerosis and arterial thrombosis, as well as myocardial infarction, ischemic stroke, and diabetic angiopathy. The occurrence of hyperhomocysteinemia is promoted by a deficiency in the body of vitamins B6 and B12.

Normalizing the level of homocysteine ​​in the blood against the background of the complex use of these vitamins prevents the progression of atherosclerosis and thrombosis, alleviates the course of coronary heart disease, cerebrovascular accidents and diabetic angiopathy.

Indications

In adults in complex therapy:

— coronary heart disease;

— cerebrovascular insufficiency of atherosclerotic origin;

- diabetic angiopathy.

Hyperhomocysteinemia.

Contraindications

- hypersensitivity to the components of the drug.

Dosage

Side effects

Allergic reactions.

Drug interactions

Folic acid. Reduces the effect of phenytoin (increasing its dose is required).

Cannot be combined with drugs that increase blood clotting.

Conditions for dispensing from pharmacies

The drug is approved for use as a means of OTC.

Storage conditions and periods

Store in a dry place, protected from light, out of reach of children, at a temperature not exceeding 25°C. Shelf life – 3 years. Do not use after the expiration date indicated on the package.

IN modern world The problem of conceiving, bearing and giving birth to a healthy child is becoming more and more urgent. Most gynecologists consider it necessary to prepare for the birth of a healthy baby long before its appearance. One of the most popular drugs used during pregnancy planning is Angiovit. We invite you to find out why and how Angiovit is used during pregnancy planning. Perhaps this information is important to you.

Angiovit (from “angio” - vessels and “vita” - life) is a complex composition of B vitamins.

This drug contains:

  • vitamin B12 (cyanocobalamin) – 6 mcg;
  • vitamin B9 (folic acid) – 5 mg;
  • vitamin B6 (pyridoxine hydrochloride) – 4 mg;
  • glucose (as an additional component).

Let's figure out what effects the individual component vitamins of Angiovit have:

  • Vitamin B12 (cyanocobalamin) – is involved in the synthesis of amino acids, which serve as “building blocks” for building the body, is involved in the process of immunity, is important for the baby and mother in the fight against anemia, regulates metabolic processes and minimizes the risk of underdevelopment of fetal organs.
  • Vitamin B9 (folic acid) – helps prevent pathologies in the fetus such as an underdeveloped neural tube, congenital heart defects and nervous system, and developmental delays in the fetus.
  • Vitamin B6 (pyridoxine hydrochloride) – important for the baby and mother in the process of forming red blood cells, transmitters and antibodies; helps digest proteins, fats and carbohydrates, relieves irritability and alleviates toxicosis in pregnant women.

Based on the summation of all the properties of its components, it is Angiovit that is most beneficial for the development of the fetus and the preservation of the health of the expectant mother.

Angiovitis for the expectant mother

A lack of certain vitamins in the diet of future parents can lead to health problems not only for themselves, but also for their future babies. Thus, a lack of B vitamins at the time a woman is carrying a baby can have consequences in the form of:

  1. Anemia in the expectant mother and her child.
  2. Formation of developmental problems in the fetus.
  3. Hyperhomocysteinemia (increased formation of amino acids in the body).

Women with hyperhomocysteinemia are at risk. This substance is toxic to the vascular-placental system and leads to disruption of the blood circulation of the placenta itself.

This condition is the most severe complication of vitamin B deficiency. Its consequence is placental insufficiency in the fetus. Even before birth, this pathology can cause oxygen starvation, leading to the death of the unborn baby. If the baby is nevertheless born, he will be weakened and prone to many ailments. The main consequences of hyperhomocysteinemia are the following situations:

  • thrombosis and development urolithiasis in pregnant women;
  • repeated (chronic) miscarriage;
  • weight loss in newborns;
  • decreased body weight and immune reserve, disorders of the nervous system in newborns;
  • pathologies of newborns in the form of encephalopathy, torticollis, hip dysplasia.

Taking Angiovit by a potential mother at the stage of pregnancy planning helps prevent severe developmental defects in newborns: developmental delay, neural tube defect, anencephaly, cleft lip, etc.

Angiovita is also prescribed to women who dream of becoming pregnant and have a history of various previous obstetric complications. It is highly advisable to take this drug to patients who have a genetic tendency to serious cardiovascular pathology in at a young age(manifested by stroke, heart attack, thrombosis, diabetes, atherosclerosis, angina pectoris).

Angiovitis for the future father

Poor male health can negatively impact a man's fertility. As you know, it is the man who often becomes the cause of infertility in marriage. Most often, the causes of this disorder are associated with a decrease in sperm quality. Angiovitis in many situations can help a man conceive a baby naturally, as it has the following effects on sperm:

  • increases their speed;
  • reduces vascular permeability;
  • increases the number of sperm with the correct set of chromosomes, significantly reducing the percentage of low-quality ones.

Thanks to its complex effect on a man’s genetic material, Angiovitis helps maintain male health and conceive healthy offspring. In addition, Angiovit allows you to prevent the future father from various cardiovascular diseases(atherosclerosis, thrombosis, stroke, myocardial infarction, diabetic angiopathy, etc.)

Taking Angiovita when planning pregnancy

Angiovitis is a common companion for couples planning pregnancy. Most often, the need to prescribe the drug during the planning period is dictated by an increase in the levels of methionine and in the body of the expectant mother.

In case of such failures, a woman is included in a certain risk group and needs medical supervision and medication support.

To obtain competent information about Angiovitis when planning pregnancy, there are clear instructions for its use during this period. However, for each patient, the doctor calculates all the details of taking this multivitamin drug.

In what dose is Angiovit prescribed when planning pregnancy?

Guided by the regimen for taking the drug described in the instructions for it, the doctor nevertheless adjusts the dose and duration of taking Angiovit for a woman or man, taking into account their state of health, weight and age.

Angiovitis can be prescribed as medicinal support when planning pregnancy:

  1. To prevent possible complications during this period, women are usually prescribed 1 tablet of medication per day.
  2. Taking the medicine is not associated with food intake and can occur at any time of the day.
  3. The course of treatment can last from 20 days to 1-2 months.
  4. If a woman still has high levels of homocysteine ​​and methionine, the use of Angiovit can continue throughout the first trimester of pregnancy.
  5. It is possible to increase the dose of the drug when treating an existing disease in a woman at the time of planning or pregnancy itself. The control for adjusting the use of the drug is the results of a detailed blood test. Any revision of the dose or regimen of use of the drug requires consultation with a gynecologist and hematologist.

Contraindications

Prescribing Angiovit when planning pregnancy rarely has any contraindications.

The only obstacles to prescribing the drug during this period are the state of individual sensitivity to B vitamins or glucose. However, this happens extremely rarely.

Side effect of Angiovitis

Although the use of the drug has a minimum of contraindications, side effects when taking Angiovitis it is not at all uncommon. Most often, such phenomena occur when the drug dosage or duration of administration is exceeded.

A side effect from using Angiovit can manifest itself as:

  • irritation or itching of the skin;
  • phenomena of urticaria;
  • Quincke's edema;
  • angioedema.

Usually all of the above manifestations disappear after discontinuation of the drug.

Drug overdose

Most often, a drug overdose can be asymptomatic. But sometimes increasing the dose of this medicine can occur in the form of symptoms:

  • dizziness or migraine-like headache;
  • skin hypersensitivity;
  • dyspeptic manifestations (bloating, nausea, stomach pain);
  • sleep disorders;
  • states of anxiety.

Sometimes women start taking Angiovit on their own after reading laudatory reviews about the drug on the Internet. At the same time, uncontrolled use of this medicine can provoke hypervitaminosis of B vitamins, the symptoms of which may manifest as:

  1. feelings of numbness in the arms and legs, problems with fine motor skills (with excess vitamin B6).
  2. thrombosis of the capillary network or anaphylactic shock (at the highest possible concentration of vitamin B12 in the blood).
  3. constant cramps of the lower extremities (with an excess of vitamin B9).

All phenomena of an excess of vitamins can only occur if the instructions for taking Angiovitis are grossly violated. In this case, it is necessary to urgently discontinue the drug and seek medical advice.

Drug interactions

Often, before planning a pregnancy, a woman may be prescribed various medications to treat existing chronic ailments.

A woman who is serious about her own health and the health of her unborn baby will definitely consult about the possibility of combining Angiovitis with other medications she is taking.

Seemingly harmless, Angiovitis, in combination with others medicines, may have the following effect:

  1. with thiamine – increase the risk of allergic reactions;
  2. with analgesics, antacids, estrogens, anticonvulsants - reduce the amount of folic acid;
  3. with antitumor and antimalarial drugs – reduce the effectiveness of folic acid;
  4. with diuretics – their effect is enhanced;
  5. with potassium preparations, salicylates, antiepileptic drugs - the absorption of vitamin B12 is reduced.

The combination of Angiovit with cardiac glycosides, aspartame and glutamic acid is beneficial due to increased myocardial contractility and increased resistance to hypoxia.

Angiovitis is valued in obstetrics due to its proven serious preventive effect for the expectant mother and her baby. Angiovit is also indicated for men as a means of improving the quality and viability of sperm. But we must not forget that violating the regimen of using this drug and taking it without authorization may result in harm to the patient instead of benefit.